EFFECT OF EUGENOL EMULSION IN POLYSORBATE-80 ON CLINICAL STRAINS OF CANDIDA ALBICANS

Candida albicans occupies a dominant position in the list of causative agents candidal lesions ear. The development new antifungal agents, an alternative source which can be herbal essential oils and their components, remains priority. One such agent with antiseptic, anti-inflammatory, analgesic action is eugenol phenol substance. Therefore, this article was aimed to study effectiveness emulsified Polysorbate-80 against clinical strains C. isolated from patients external otomycosis. performed using 6 ear canal otitis externa. diagnosis fungal disease established based on results laboratory (microscopical mycological) studies pathological material. Analysis mycological research showed that mainly representatives genus Aspergillus Penicillium were revealed only 7% there fungi. remained species significance. our high level activity all albicans, including remarkable inhibitory fungicidal effect. At postmycostatic concentrations, caused partial inhibition reproduction fungi, replaced by subsequent increased cell rate. So, investigation has shown among fungi structure microbial profile otomycoses. eugenol, Polysorbate-80, effect albicans. increase